The Family That Couldn't Sleep: A Medical Mystery By D.T. Max

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For two hundred years a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future. Through exclusive interviews and original archival research, Max explains this story’s connection to human greed and ambition–from the Prussian chemist Justus von Liebig, who made cattle meatier by feeding them the flesh of other cows, to New Guinean natives whose custom of eating the brains of the dead nearly wiped them out. The biologists who have investigated these afflictions are just as extraordinary–for example, Daniel Carleton Gajdusek, a self-described “pedagogic pedophiliac pediatrician” who cracked kuru and won the Nobel Prize, and another Nobel winner, Stanley Prusiner, a driven, feared self-promoter who identified the key protein that revolutionized prion study.With remarkable precision, grace, and sympathy, Max–who himself suffers from an inherited neurological illness–explores maladies that have tormented humanity for centuries and gives reason to hope that someday cures will be found. And he eloquently demonstrates that in our relationship to nature and these ailments, we have been our own worst enemy.

At this time of writing, The Mobi The Family That Couldn't Sleep: A Medical Mystery has garnered 10 customer reviews with rating of 5 out of 5 stars. Not a bad score at all as if you round it off, it’s actually a perfect TEN already. From the looks of that rating, we can say the Mobi is Good TO READ!

Audio Book The Family That Couldn't Sleep: A Medical Mystery with Free PDF EDITION!

I found this book to be incredibly interesting. I teach biology and anatomy to nurses, and I've known about prion diseases for a long time. I had read before about the disease kuru in New Guinea, and about the Mad Cow outbreak in Great Britain. But reading about a family that has an inherited disease that involves prions really changes things a bit in this field. In medical school, we heard of a case where surgeons opened the skull of a patient, thinking he had Alzheimer's Dementia...only to find out the person had Crutzfeld-Jakob disease. The proper protections were not in place and other people got infected with it.Prion diseases are different, in that they are not caused by bacteria or viruses, which we have known about for over 100 years. Prions are pure protein, and we have them in our brains normally. But when diseased prions touch normal proteins, they cause the unfolding of those proteins. And this causes the misfunction of normal proteins.I feel for this family in Italy. Their condition, that plagues their family, curbs their lives. But doctors will find out a lot more about prions by observing this family. Their misfortune will add to the current medical knowledge of the world about prions.

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